Selman Ali Dokumacı

Selman Ali Dokumacı

Independent Researcher

Computational BiophysicsMolecular EngineeringScientific Computing

Introduction

Independent researcher focusing on computational biophysics and molecular engineering.

Current work centers on designing condition-responsive protein systems using atomistic simulation, elastic network analysis, and thermodynamic modeling.

Selected Research

Condition-Responsive Therapeutic

MACS: Modular Activated Cancer Suppressor

Single-mRNA-Encoded Multi-Domain Protein System with Acidic Microenvironment-Responsive Logic Gating

Full project record

Domain-Specific Architecture

MDX: Molecular Dynamics Accelerator

A correctness-first, pre-silicon domain-specific accelerator architecture for classical molecular-dynamics workloads.

Full project record

Research Areas

Computational Structural Biology

Atomistic molecular dynamics, conformational analysis, and structure-function relationships in engineered protein systems.

Condition-Responsive Therapeutics

Design principles for biotherapeutics that discriminate between healthy and diseased microenvironments through physicochemical gating.

Scientific Computing & Accelerator Architecture

Correctness-first reference models and domain-specific architectures for molecular-dynamics and scientific-computing workloads.

Reports & Technical Documentation

Technical documentation supporting the research records above.
Year Title Document type Project Access
2026 MACS Mechanistic Evidence Summary Technical Report MACS Read
2026 MACS Methodological Decision Log Technical Documentation MACS Read
2026 MACS Mechanistic Evidence Matrix Technical Documentation MACS Read
2026 MDP Consistency Report Technical Documentation MACS Read

Inventions & Intellectual Property

Modular Synthetic Transmembrane Biological System Enabling Conditional Activation and Protein Degradation Based on Molecular Marker Density

Status
National Patent Application Filed
Jurisdiction
Turkey (TURKPATENT)
Inventor
Selman Ali Dokumacı

Publicly available filing information. Details omitted pending publication.

About

Research conducted independently, with computational resources including local GPU workstations and high-performance computing access.

Profiles & Contact

For academic collaboration, research inquiries, or professional communication, reach out through the following channels:

Note: Research-related inquiries are prioritized. LinkedIn is recommended for initial contact.